胃潰瘍吃什麼？試試沙棘油功效：胃潰瘍、嘴破、燒傷治療

资讯 2024-07-15 阅读:47 评论:0

沙棘在治療傷口上有著淵源流長的歷史。在外科手術不發達的時代，老祖宗們透過外敷及內用沙棘油緩解創口帶來的不適症狀，例如燒傷、潰瘍、黏膜破損等，作為一個古老藥草，沙棘在修復上皮組織的表現可說是十分稱職。而時序推展至今日，科學家們以實驗證實沙棘...

沙棘在治療傷口上有著淵源流長的歷史。在外科手術不發達的時代，老祖宗們透過外敷及內用沙棘油緩解創口帶來的不適症狀，例如燒傷、潰瘍、黏膜破損等，作為一個古老藥草，沙棘在修復上皮組織的表現可說是十分稱職。而時序推展至今日，科學家們以實驗證實沙棘的效用不僅只是傳說。

There is a history of sarcophagus flow in the treatment of the wounds. In times of non-surgical surgery, ancient ancestors have been able to experiment to prove the utility of sarcophagus not only as an ancient herb, but also as a mirage, and as a mucous membranes.

胺甲蝶呤Methotrexate(MTX)是一種化療藥物，其機轉為阻止身體利用葉酸而達到治療惡性腫瘤的效用。但使用MTX會伴隨多種副作用例如噁心、倦怠、皮疹、肝腎毒性及口腔黏膜受損。今以MTX誘導大鼠口腔黏膜損傷，進以餵食沙棘提取物(HRE)[1]，觀察修復結果。

Methotrexate (MTX) is a chemotherapy drug that has shifted to preventing the body from using folic acid for the treatment of malignant tumors. But the use of MTX is accompanied by multiple side effects such as nausea, weariness, rash, liver and kidney toxicity, and oral mucous membrane damage. Today MTX induces rats to mucouple damage by feeding , observing the recovery results.

下圖一、二、三分別測試犧牲後大鼠在頰邊黏膜、下唇及舌部的MDA、tGSH、IL-1β、TNF-α。監測組織的生化指標得出結論，HMTX皆優於MTXC組，tGSH較高，MDA、IL-1β、TNF-α較低。

Figures I, II, and III below show that rats have lost MDA, tGSH, IL-1beta, and TNF-α on their cheeks, lower lip and tongue. The biochemical indicators of the monitoring organization conclude that HMTX is higher than the MTXC, higher tGSH, lower MDA, IL-1beta, and lower TNF-α.

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表一、健康組(HG)、HRE+MTX組(HMTX)、MTX組(MTXC)

組別	HG	HMTX	MTXC
第一次餵食	50mg/kg蒸餾水	50mg/kg HRE	50mg/kg蒸餾水
間隔時間	一小時
第二次餵食	5mg/kg蒸餾水	5mg/kg MTX	5mg/kg MTX
持續餵食時間	一個月

Table I, Health Group (HG), HRE+MTX Group (HMTX) "MTXC"

圖一、大鼠在頰邊黏膜MDA、tGSH、IL-1β、TNF-α

br/> figure I; rats with mucous membrane MDA, tGSH, IL-1b, TNF-α on their cheeks

圖二、大鼠在下唇黏膜MDA、tGSH、IL-1β、TNF-α

br/> figure II; rats in the lower lip viscous MDA, tGSH, IL-1B, TNF-α

圖三、大鼠在舌部MDA、tGSH、IL-1β、TNF-α

br/>figure III; rats in tongue MDA, tGSH, IL-1B, TNF-α

圖四、以顯微鏡監測組織切片的生理圖面

br/> figure IV, microscopic monitoring of the physiography of the tissue slices

排序由左至右，由上至下分別是A~LHG組的臉頰、下唇和舌頭其組織無任何不良症狀(圖4a,4b,4c)、HMTX組分別顯示在臉頰、下唇和舌頭出現水腫(星型)、擴張的充血血管(箭頭)(圖4d,4e,4f)，而圖4g、4h、4i進一步監測MTXC組在舌部的纖維細胞增生、脂肪細胞取代肌肉層和增生血管的情形。而經過HRE處理的HMTX組，其臉頰、下唇和舌頭的組織切片與HG的組別無明顯差異(圖4j、4k、4l)。

The order is from the left to the right, and the top to the bottom is the A-LHG's cheeks, lower lip and tongue tissues are free of any adverse symptoms (figures 4a, 4b, 4c), HMTX's composition shows aluminous presence in the cheeks, lower lip and tongue (star type), expanded blood vessels (arrowheads) (figures 4d, 4e, 4f), while figures 4g, 4h, 4i further monitor the growth of the MTXC's hysteria in the tongue, the replacement of muscles and boosted blood vessels by fat cells. The HMTX's tissue slices of cheeks, lower lips and tongues treated by HRE do not differ significantly from the HG's composition (figures 4j, 4k, 4l).

化療會造成體內抗氧化物質(如維生素E)的流失，抗氧化物質的補充可增加化療殺死癌細胞的效果也能保護正常細胞不被破壞。由於沙棘含有維生素A、E、C、胡蘿蔔素、類黃酮等等，推測是這些抗氧化物質保護下而抵禦MTX造成的黏膜傷害。而沙棘中的棕櫚油酸、油酸以及亞麻油酸也抑制了組織中促發炎因子IL-1β、TNF-α。

The chemotherapy causes the loss of internal antioxidants (e.g. vitamin E), and the antioxidation supplement increases the ability of chemical antioxidants to kill cancer cells and protects normal cells from destruction. 上一篇文章提到[2]，沙棘果油和沙棘籽油脂肪酸組成不同，但在治療乙酸誘導的胃潰瘍效果上沒有顯著差異。推測其抗潰瘍作用可能非單一脂肪酸所致。這些油中含有大量的β-胡蘿蔔素，α-生育酚和β-谷固醇。β-谷固醇已被證明對乙酸誘導的胃潰瘍有治癒作用。

In addition to the restoration of the oral mucus membrane, the sarcophagus also contributes significantly to the damage to the stomach. in the previous article /a> refers to , which differs from the sardine oils and sardine oil fat acids, but there are no significant differences in the treatment of adipose acid.

另外也有證據顯示沙棘油能抑制胃潰瘍病灶的脂質過氧化作用、增加粘膜表面疏水性、抑制胃液分泌和蛋白酶活性以及促進黏膜細胞再生。

There is also evidence that Sarcand oil inhibits lipid peroxidation of gastroenterosis stoves, increases mucous surface hydration, inhibites gastric fluid and protein enzyme activity, and stimulates mucous cell regeneration .

最後一篇文獻 [3]是探討沙棘萃取物對酒精引起大鼠胃潰瘍的效用。乙醇是眾所皆知會增加胃潰瘍風險的危險因子之一，如同飲酒過量會傷胃，乙醇會增加胃部黏膜的通透性引起血管損傷及胃部細胞壞死，而體內的抗氧化物:穀胱甘肽(GSH)則可保護細胞免於乙醇造成的氧化壓力。

The last article is a exploration of the effect of sarcine extraction on alcohol in the stomach of rats. ethanol is known to be one of the risk factors for increasing stomach risk, as excessive alcohol consumption can cause gastrophy, ethanol increases the permeability of the glutinous membranes in the stomach leading to blood damage and gastrophy, while antioxidation in the body: gluc glycone (GSH) protects cells from the oxidation pressure of ethanol.

今以沙棘萃取物(HRe-1)、褪黑激素(Melatonin)、奧美拉唑(Omeprazole)、乙醇(Ethnol)及控制組(Control)分別餵食大鼠。

Today, there is a distinction between the sarcophagus (HRe-1), melatonin, Omeprazole, Ethnol, and the control group (Control) feeding rats.

表二、大鼠胃部潰瘍指數和胃部潰瘍面積

Table II. Rat stomach hysteria index and stomach tummy

圖五、不同組別其胃部GSH含量

奧美拉唑是常見的治療消化道潰瘍的口服用藥。其機轉是抑制質子幫浦，降低胃中酸性避免潰瘍擴大。值得注意的是沙棘萃取物在潰瘍指數、減少潰瘍面積及病灶處GSH的含量都優於奧美拉唑。綜述以上文獻，不管是內服或外用，沙棘果油對口腔、消化道的黏膜損傷確實有修復的效用。胃潰瘍吃什麼？試試看沙棘油吧！

Omelazole is a common oral drug for the treatment of digestive tracts. The possibility is to suppress the Qur'an, reducing acidity in the stomach, and avoiding the expansion of the sarcophagus. It is worth noting that the sarcophagus extracts have a better content than Omera sulfur. [4]

Studies show that sarcophagus seed oils are effective in treating burns. Nearly 90% of the sarcophagus seeds are unsaturated and fatty acids, including alpha-subsaline oilic acids (-3), nitrous acids (6), oily acids (9) and palm oilic acids (7). This is attributable to high levels of vitamin E, thorium-like thorium, plant salamiols, and polysaturates and fatty acids (3 and 6). These plant components can provide protection and nutrients for injured tissues.

棕櫚油酸是皮膚的一種成分，可外敷治療燒傷和癒合傷口。口服棕櫚油酸還可以滋養皮膚。沙棘籽油可抑制蠟狀芽孢桿菌，凝結芽孢桿菌，枯草芽孢桿菌，單核細胞增生李斯特菌和腸球菌耶爾森氏菌生長。其抗菌作用具有降低燒傷感染的潛力[5]。

Palm oil acid is a component of skin that can be treated for burns and healing. its resistance has the potential to reduce burns

實驗指出沙棘籽油以口服2.5ml/kgw和外用處理傷口7天，可促進明顯的上皮再生和傷口閉合。與用1％磺胺嘧啶銀軟膏治療的對照組和控制組相比，沙棘籽油組增強燒傷創面中肉芽組織和膠原蛋白合成。沙棘籽油可能與傷口部位的成纖維細胞和角質形成細胞增殖有關。它具有增加新的毛細血管形成的能力，通過肉芽組織的形成有助於結構修復 [6]。

The experiment indicates that the sarcophagus seed oil is used for an oral treatment of 2.5 ml/kgw and external treatment wounds for seven days, which induces clear upper skin regeneration and condensation of wounds. Compared to the sulfadine silver cream treatment of 1%, the sardine seed oils have enhanced the sorghum tissue and the plough protein synthesis in the face of the burns. The sardine seed oil may be associated with cellular growth in the cellular cells and horns of the wound. It has the capacity to increase the formation of new ceremonial veins and contribute to reconstruction through the formation of sprouts [6]/a>.